Center for Advanced Practice

Publication Title

J Am Heart Assoc

Document Type

Article

PubMed ID

33317366

Abstract

Background The physiologic hallmarks of the Fontan circulation-chronically elevated central venous pressures and low cardiac output-have significant effects not only on cardiovascular status but also impact other organ systems. Exercise capacity is limited in many and declines with age, accelerating in adolescence, but with wide variability. We explore the relationship between exercise performance and end-organ function in outpatient subjects with a Fontan circulation. Methods and Results This is a cross-sectional analysis of subject end-organ characterization from our outpatient Fontan circulation clinic with peak oxygen consumption (peak Vo

Keywords

Adolescent, Child, Cross-Sectional Studies, Exercise Test, Exercise Tolerance, Female, Fontan Procedure, Heart Defects, Congenital, Hemoglobins, Humans, Liver Function Tests, Male, Multiple Organ Failure, Oxygen Consumption, Retrospective Studies, Vitamin D

DOI

10.1161/JAHA.120.016850

Publication Date

12-15-2020

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