Title

Study protocol for a two-center test of a nurse-implemented chronotherapeutic restoring bundle in critically ill children: RESTORE Resilience (R

Authors

Mallory A Perry
Onella S Dawkins-Henry
Ronke E Awojoodu
Jennifer Blumenthal, Children's Hospital of Philadelphia, Philadelphia, PAFollow
Lisa A Asaro
David Wypij
Sapna R Kudchadkar
Athena F Zuppa, Children's Hospital of Philadelphia, Philadelphia, PAFollow
Martha A Q Curley, Children's Hospital of Philadelphia, Philadelphia, PAFollow

Publication Title

Contemp Clin Trials Commun

Document Type

Article

PubMed ID

34466711

Abstract

Often, pediatric intensive care environments are not conducive to healing the sick. Critically ill children experience disruptions in their circadian rhythms, which can contribute to delayed recovery and poor outcomes. We aim to test the hypothesis that children managed via

CLINICALTRIALSGOV IDENTIFIER: NCT04695392.

Keywords

CINC, Community in nursing care, circadian rhythm, DARE, daytime activity ratio estimate, DCC, data coordinating center, DMS, data management system, EEG, electroencephalography, FCCS, family-centered care scale, ICU, intensive care unit, mechanical ventilation, nurse-implemented interventions, PCPC, pediatric cerebral performance category, pediatric critical care, PICU, pediatric intensive care unit, POPC, pediatric overall performance category, PRISM III-12, pediatric risk of mortality III score from, WAT-1, withdrawal assessment tool-1

DOI

10.1016/j.conctc.2021.100840

Publication Date

9-1-2021

Citation

Perry, M., Dawkins-Henry, O., Awojoodu, R., Blumenthal, J., Asaro, L., Wypij, D., Kudchadkar, S., Zuppa, A., & Curley, M. (2021). Study protocol for a two-center test of a nurse-implemented chronotherapeutic restoring bundle in critically ill children: RESTORE Resilience (R. Contemp Clin Trials Commun, 23, 100840-100840. https://doi.org/10.1016/j.conctc.2021.100840